[FILM-Users 00412] FW: Webinar: Optical and microCT Imaging of Bacteria, Viruses and Tumors

[Martin Spitaler]

...forwarded for your information,

Martin
"Phenotyping TILs in situ: The enumeration and quantitation of 
phenotypic subsets of immune cells in tissue sections"

*From:*SelectScience [mailto:product-news at selectscience.net]
*Subject:* Webinar: Optical and microCT Imaging of Bacteria, Viruses and 
Tumors

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Webinar Ivis Imaging

	

	

Attend our Live Webinar *
*Optical and microCT Imaging of Bacteria, Viruses, and Tumors **

Examples of temporal and spatial analyses of various luminescent and 
fluorescent reporters /in vivo, ex vivo/ and /in vitro/ will be described.

Tuesday, October 8, 2013 | 10 am Pacific | 1 pm Eastern | 6 pm GMT

Register Now 
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The key to cancer therapy utilizing microbes is the ability to track the 
spread and replication of the bacteria or viruses within the body over 
time. A number of strategies employing IVIS^® optical imaging for 
tracking reporter constructs in different models, from /in vitro/ 
through to clinical samples have been developed. For bacterial work, 
novel /lux/ reporter constructs for luminescence imaging of different 
genera /in vitro/ and /in vivo/ in mice have been generated. This has 
permitted 2D and 3D whole body imaging for a wide range of both invasive 
and non-invasive species in different anatomical settings– in tumors, 
various deep organs, and even within the gastrointestinal tract of live 
animals.

For eukaryotic work (tumors or viruses), luciferase tagged constructs 
permit similar imaging, the ability to monitor different luminescent 
reporters simultaneously (e.g. lux + Fluc within the same tumor), 
providing highly detailed monitoring of infections and host responses 
has been demonstrated.

Additionally, techniques for luminescence imaging of microbes and gene 
delivery in patient tissue /ex vivo/ to provide clinically relevant data 
have been developed.

	

Presented by:

*Mark Tangney PhD. *
Principal Investigator, Cork Cancer Research Centre, University College 
Cork, Ireland

Mark

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