[FILM-Users 00434] FILM application for Wellcome Trust Multi-User Equipment grant

[Martin Spitaler]

Dear microscopists,

    following feedback from FILM users and Wellcome Trust grant holders 
(see summary at the bottom), the FILM steering committee has decided to 
use the open call for Wellcome Trust Multi-User Equipment grant 
applications to apply for upgrades / updates of existing equipment as 
well as some novel technology. The highest demand is currently for a new 
super-resolution microscope, which is luckily already funded by BBSRC, 
we are now in the process of testing the equipment to be purchased. 
Other demands stretched across a wide range of technologies and 
unfortunately also locations across the college, the committee tried to 
strike the best balance between all needs and decided to apply for the 
following package:

  * _New technology_:
      o an *automated high-throughput **m**icroscopy* system (e.g.
        Operetta or similar)
      o the high-throughput capacity, in combination with existing image
        processing / analysis capacity (e.g. Definiens) will satisfy the
        needs for both the high-content screening and to a large degree
        ImageStream needs
  * _Upgrade_:
      o *upgrade of the existing intravital microscope (FILM-CF3)* with
        options including high-sensitivity hybrid detectors, 405 laser,
        a cabinet for mouse handling, laser dispersion correction
        (detailed options to be checked with manufacturers)
  * _Support_:
      o *one full-time FILM staff post for Hammersmith* for the duration
        of the grant
  * _Replacement_:
      o *a high-sensitivity new-generation confocal* (similar to the
        Zeiss LSM-780 in Hammersmith), to be located in SAFB / South
        Kensington
  * _Possible options for small, complementary equipment add-ons_:
      o FleXcell Tensions System
      o ONIX microfluidic platform (if not already funded by other
        sources through other sources)
      o a high-precision multi-channel peristaltic pump system


   Obviously, we can't apply for everything on the list at the same 
time, some things will have to wait for the next equipment grant call.

  We now need to finalise the application - and for that *we need your 
support*: Those of you willing to support the application with your 
scientific interest and track record, please do get back to us soon - 
the deadline for the preliminary application is 2nd of December.
    And although the major bits of equipment to go on the application 
have been decided, if there are smaller add-ons missing on the list that 
would help with your microscopy in FILM, please let us know.

Good imaging,

Martin

_*Information:
*_

  * http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-schemes/Strategic-awards-and-initiatives/WTDV031728.htm


_*Summary of **m**icroscopy needs in Imperial College - FILM, feedback 
2013*:_





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