[FILM-Users 00447] TODAY: Eric Betzig lecture super-resolution and light sheet microscopy on 11th December 2013
Martin Spitaler
m.spitaler at imperial.ac.uk
Wed Dec 11 09:27:23 GMT 2013
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Subject: Eric Betzig lecture super-resolution and light sheet micrscopy
on 11th December 2013
Date: Tue, 5 Nov 2013 15:35:16 +0000
From: French, Paul (PHOT) M W (Photonics) <paul.french at imperial.ac.uk>
To: Spitaler, Martin <m.spitaler at imperial.ac.uk>
Dear Martin,
Eric Betzig is one of the leading pioneers of both PALM microscopy for
super-resolved imaging and light sheet microscopy for rapid imaging of
live organisms. This promises to be an excellent talk. Please could
you advertise it, e.g. through your FILM mailing list and the London
super-resolution club.
Best wishes,
Paul
Leica Scientific Forum UK presents Eric Betzig
*Wednesday, December 11, 2013 at 17:00h - Chair: Paul French*
Venue: Imperial College London, Lecture Theatre 3, Blackett Laboratory,
Prince Consort Road, London SW7 2BB
Eric Betzig <http://www.janelia.org/lab/betzig-lab>
Janelia Farm Research Campus, Howard Hughes Medical Insitute,
Ashburn, VA
"Imaging Life at High Spatiotemporal Resolution"
Optical microscopy has remained at the forefront of biological discovery
for centuries. However, as our understanding of biological systems as
increased, so has the complexity of our questions and the need for more
advanced optical tools to answer them. For example, there is a
hundred-fold gap between the resolution of conventional optical
microscopy and the scale at which molecules self-assemble to form
sub-cellular structures.
Furthermore, as we attempt to peer more closely at the dynamic
complexity of living systems, the actinic glare of our microscopes can
adversely influence or even kill the specimens we hope to study.
Finally, the heterogeneity of life, ranging from organelles within
single cells to specialized cell types within tissues and organs, can
seriously impede our ability to image at high resolution, due to the
resulting warping and scattering of light rays.
I will describe three areas focused on addressing these challenges:
super-resolution microscopy for imaging specific proteins within cells
down to near-molecular resolution; plane illumination microscopy using
non-diffracting beams for noninvasive imaging of three-dimensional
dynamics within live cells and embryos; and adaptive optics to recover
optimal images from within optically heterogeneous specimens
Invitation poster:
<https://workspace.imperial.ac.uk/imagingfacility/Public/seminar.pdf>
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